The development of non-coding RNA ontology

Jingshan Huang, Karen Eilbeck, Barry Smith, Judith A Blake, Dejing Dou, Weili Huang, Darren A Natale, Alan Ruttenberg, Jun Huan, Michael T Zimmermann, Guoqian Jiang, Yu Lin, Bin Wu, Harrison J. Strachan, Nisansa de Silva, others
International journal of data mining and bioinformatics

Identification of non-coding RNAs (ncRNAs) has been significantly improved over the past decade. On the other hand, semantic annotation of ncRNA data is facing critical challenges due to the lack of a comprehensive ontology to serve as common data elements and data exchange standards in the field. We developed the Non-Coding RNA Ontology (NCRO) to handle this situation. By providing a formally defined ncRNA controlled vocabulary, the NCRO aims to fill a specific and highly needed niche in semantic annotation of large amounts of ncRNA biological and clinical data.

Keywords: Bioinformatics | Ontologies | Non-coding RNA | Biomedical Ontology | Ontology Development | Data Annotation | Semantic Data Annotation | Domain Ontology | Reference Ontology |